As it happened: Injured Nadal knocked out; Kokkinakis advances on brutal night for Australians; Swiatek, Tsitsipas, Medvedev, Gauff progress

Mackenzie McDonald has knocked Rafael Nadal out of the Australian Open.

Nadal was clearly ailing after appearing to injure his leg late in the second set, which saw him call an injury time-out and seek treatment.

He battled on, but couldn’t lunge or reach for shots as the 27-year-old American scored the biggest win of his career.

McDonald wins 6-4, 6-4, 7-5.

The loss had similarities to Nadal’s Wimbledon campaign last year where he battled through injury to beat American Taylor Fritz in the quarterfinals but couldn’t play in the semis due to his injury.

American Danielle Collins has fought off a challenge from Czech player Karolina Muchova, beating her in three sets in a hard-fought match that lasted almost three hours.

Collins broke first in the third set, and Muchova broke back straight away. Nothing could split them, which led them to a tiebreaker.

Collins, whose left leg was heavily strapped, prevailed 10-6 as the final set went for 80 minutes.

Collins bt Muchova 7-6 (7-1), 2-6, 7-6 (10-6)

Meanwhile, 10th seed Hubert Hurkacz defeated Italian Lorenzo Sonego on Court Three, in a match that went to five sets.

Hurkacz bt Sonego 3-6, 7-6 (7-3), 2-6, 6-3, 6-3.

Polish 10th seed Hubert Hurkacz has forced his second-round match into a fifth and deciding set after winning the fourth against Italy’s Lorenzo Sonego.

The contest on show court three is now evenly poised at 3-6, 7-6 (7-3), 2-6, 6-3 after three hours and 13 minutes.

Meanwhile, American 13th seed Danielle Collins has broken the Czech Republic’s Karolina Muchova in the third set to lead 6-7 (1-7), 6-2, 3-2 at Margaret Court Arena.

And on show court three, British 11th seed Cameron Norrie is all tied up with France’s Constant Lestienne 6-3, 3-6, 5-5.

Denis Shapovalov is through to the third round after defeating Japan’s Taro Daniel in straight sets.

Taro put up a fight in the second set, which went to a tiebreaker. He also forced the third set into a 12th game, but 20th seed Shapovalov prevailed; winning 7-5.

He will now play either 10th seed Hubert Hurkacz or Lorenzo Sonego in the next round.

Shapovalov bt Taro 6-3, 7-6 (7-3), 7-5.

Meanwhile, 13th seed Danielle Collins has hit back to win the next set, after a shaky start against unseeded Czech player Karolina Muchova.

Collins won the second set in 38 minutes, 6-2, after losing the first in a tiebreak 7-6 (7-1).

Two-time Australian Open champion Victoria Azarenka has quickly taken the first set in her second-round match against Argentina’s Nadia Podoroska 6-1 in just 29 minutes at Kia Arena.

Podoroska was her own worst enemy, tripling Azarenka for unforced errors (15-5) and cancelling out the fact that she almost doubled the 24th seed for winners 7-4.

Meanwhile, Polish 10th seed Hubert Hurkacz has a fight on his hands, trailing Italy’s world No.47 Lorenzo Sonego 6-3, 6-7 (3-7), 6-2 in their second-round match on show court three.

And after winning the first set 6-3, British 11th seed Cameron Norrie has been broken in the second set of his second-round match with world No.55 Constant Lestienne and trails the Frenchman 4-3 on show court 13.

Twentieth seed Denis Shapovalov has narrowly taken a second set against Japan’s Taro Daniel after a tiebreak on 1573 Arena.

The Canadian won the first set 6-3, but Daniel fought back in the second, forcing a tiebreak that was then paused due to rain.

Shapovalov won the set 7-6 (7-3).